Live 2020

As Canada enters its third month of disruption due to the COVID-19 pandemic, social problems such as loneliness and stigmatization become more apparent. A study published by Dr. Lesley Fellows at The Neuro, together with colleagues Dr. Marie-Josée Brouillette and Nancy Mayo at the Research Institute of the McGill University Health Centre and investigators at sites across the country, provides a portrait of loneliness linked to another devastating virus – the human immunodeficiency virus, or HIV.
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Live 2020

The McGill Interdisciplinary Initiative in Infection and Immunity is pleased to announce funding for an additional 20 projects in Round 2 of the MI4 Emergency COVID-19 Research Funding program. This brings the total number of ECRF projects funded to date to 36, with a total allocation of nearly $3 million in direct research funding.
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Live 2020

A simple blood test that can detect Alzheimer’s disease has been discovered and validated in a joint effort by a McGill team and researchers in Sweden. Their results are published in the May issue of The Lancet Neurology. An accompanying commentary calls the discovery “transformative.”
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Live 2020

The Montreal General Hospital Foundation and the Research Institute of the McGill University Health Centre are pleased to announce the three finalist teams for the Code Life Ventilator Challenge. Launched on March 19th, this two-week sprint to design a low-cost, simple, easy-to-use and easy-to-build ventilator that can serve patients suffering from COVID-19, has received more than 2,600 registrations, representing over 1,000 teams from 94 countries.
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Live 2020

Know your enemy,” is perhaps one of the most well-known proverbs, often quoted by military buffs and corporate leaders alike. And yet in the face of the COVID-19 pandemic this ancient saying by the strategist and philosopher Sun Tzu, takes on a vital and important meaning. In this context, the formation of the “Biobanque Québécoise de la COVID-19” (BQC19) / COVID-19 Québec Biobank, a provincial biobank initiative, on April 1 was an essential and strategic move.
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Live 2020

Many of the drugs and medicines that we rely on today are natural products taken from microbes like bacteria and fungi. Within these microbes, the drugs are made by tiny natural machines – mega-enzymes known as nonribosomal peptide synthetases. A research team led by McGill University has gained a better understanding of the structures of NRPSs and the processes by which they work. “NRPSs are really fantastic enzymes that take small molecules like amino acids or other similar sized building blocks and assemble them into natural, biologically active, potent compounds, many of which are drugs,” said Martin Schmeing, Associate Professor in the Department of Biochemistry at McGill University, and corresponding author on the article that was recently published in Nature Chemical Biology. “
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Live 2020

Dr. Mathieu Maheu-Giroux, Assistant Professor in the Department of Epidemiology, Biostatistics and Occupational Health, and colleagues, with support from the MI4 Emergency COVID-19 Research Funding program, are building a mathematical model to crunch government COVID-19 numbers to shine a light on real time transmission rates and provide short-term forecasts about hospitalizations, new cases and mortality.
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Live 2020

Life is defined by proteins and their ability to interact with one another to form complex structures, such as cells, organs and functioning organisms. A landmark study from an international team of researchers co-led by Frederic Roth of the Donnelly Centre, University of Toronto, and by Michael A. Calderwood, Marc Vidal, and David E. Hill from Harvard Medical School and Dana-Farber Cancer Center, has produced the most comprehensive blueprint to date of how all proteins interact and function in cells. Postdoctoral fellow Dongsic Choi and senior scientist Janusz Rak from the Research Institute of the McGill University Health Centre, with their University of Toronto collaborator, Dae-Kyum Kim, contributed to the study.
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Live 2020

Crises are no excuse for lowering standards of clinical research according to medical ethicists. Ethicists from Carnegie Mellon and McGill universities are calling on the global research community to resist treating the urgency of the current COVID-19 outbreak as grounds for making exceptions to rigorous research standards in pursuit of treatments and vaccines. Their paper, published online today in Science, provides recommendations for conducting clinical research during times of crises.
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Live 2020

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes. Despite their effectiveness, only 40% of patients respond to the first antidepressant they try. A recent paper in Nature Communication strongly suggests that a particular protein, GPR56, is involved in the biology of depression and the effect of antidepressants. The research team led by Professor Gustavo Turecki of McGill University and the Douglas Mental Health University Institute, believe that this protein could offer a novel target for new antidepressant drugs.
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