Live 2020

It is known that the tumour microenvironment plays an important role in the progression of cancer. But could estrogen present in this microenvironment facilitate the growth of liver metastases in women affected by colon, pancreatic and lung cancers? This is what a team of researchers from the Research Institute of the McGill University Health Centre suggests, in a study that shows for the first time that the liver immune microenvironment reacts to metastatic cells differently in male and in female mice and that, indeed, the main female hormone estrogen can indirectly contribute to the growth of metastases.
Read more ►

 


Live 2020

After seven years of collaboration, a team of researchers from the Research Institute of the McGill University Health Centre has developed an intelligent molecule that could significantly extend the lives of patients with glioblastoma, an incurable and devastating brain cancer that affects people of all ages, regardless of their lifestyle. According to the results of a study led by Dr. Siham Sabri and published in the journal Clinical Cancer Research from the American Association of Cancer Research, this molecule called ZR2002, administered orally and capable of penetrating the blood-brain barrier, could delay the multiplication of glioblastoma stem cells resistant to the standard treatment offered to patients.
Read more ►

 


Live 2020

Dr. Theresa Gyorkos, Senior Scientist in the Infectious Diseases and Immunity in Global Health Program at the Research Institute of the McGill University Health Centre, has dedicated her career to understanding and reducing the harms caused by parasitic worm infection. “The key,” she explains, “is to eliminate fecal contamination by a combination of treatment and improved household sanitation and hygiene”, a goal the World Health Organization hopes to achieve by 2030.
Read more ►

 


Live 2020

During childhood, the human brain is highly sensitive and will form connections to best adapt to its environment. This ability, called plasticity, diminishes as we age. Rebooting this ability may be the key to everything from treating neurodegenerative disease to helping the brain heal from trauma. In the lab of Dr. Etienne de Villers-Sidani at The Neuro, researchers study the fundamentals of brain plasticity. The goal of this work is to develop therapies and strategies to help neurological patients.
Read more ►

 


Live 2019

The design of the Glen site – where a pediatric and adult hospital live side-by-side – has led to a unique MUHC collaboration for the benefit of a particular pediatric patient. There are few situations where a Montreal Children’s Hospital patient would be directly impacted by the Royal Victoria Hospital. But the complexities around the treatment of one eight-year-old patient led Dr. Meranda Nakhla, a pediatric endocrinologist at the Children’s, to work directly with the RVH to find a solution.
Read more ►

 


Live 2019

For years, physicians have been aware that patients carrying the apolipoprotein ꜫ4 (APOE ꜫ4) gene are at a greater risk of developing Alzheimer’s disease. New research from McGill University has now found the gene plays an even greater role in dementia. In a study published today in the Journal of the American Medical Association: Neurology, Dr. Pedro Rosa-Neto’s research team from the Douglas Mental Health University Institute’s Translational Neuroimaging Laboratory found that the risk of developing dementia conferred by APOE ꜫ4 does in fact involve processes associated to tau aggregation.
Read more ►

 


Live 2019

In a recent issue of the journal BMJ Open, a study team led by Dr. Meranda Nakhla, a researcher at the Research Institute of the McGill University Health Centre and Montreal Children’s Hospital of the MUHC, has tackled a conspicuous gap in diabetes care. Over the next five years her team will examine group education visits as an alternative and potentially cost-effective approach to providing transition care services to adolescents living with type 1 diabetes.
Read more ►

 


Live 2019

A unique collaboration between cardiologists and radiation oncologists at the McGill University Health Centre will allow some patients with severe arrhythmias, including ventricular tachycardia, to benefit from a radiotherapy treatment consisting of accurately irradiating the abnormal parts of the heart that cause the arrhythmias.
Read more ►

 


Live 2019

Using tumor biopsies from patients with chemotherapeutic resistant triple negative breast cancer, researchers at the Lady Davis Institute of the Jewish General Hospital have identified changes to the form of the cancer cells that appear to be associated with their capacity to resist usual drug treatment. This discovery is featured on the cover of the December issue of Molecular Cancer Research, where it is highlighted for its importance.
Read more ►

 


Live 2019

In September 2019, the first position statement on exercise for Solid Organ Transplant candidates and recipients was published in the Transplantation journal. The position statement was the creation of a working group co-led by Tania Janaudis-Ferreira, a professor and researcher at the McGill University’s School of Physical & Occupational Therapy and Sunita Mathur of the University of Toronto’s Department of Physical Therapy. Dr. Janaudis-Ferreira recently took some time to answer a few questions for us.
Read more ►