Montreal-based investigator receives funding to study metastatic sarcomas, similar to the type discovered in Terry Fox

Thanks to a New Investigator award from the Terry Fox Research Institute, McGill’s Dr. Livia Garzia, is studying how and why certain sarcomas metastasize. Her hope is that by identifying early signs of metastatic dissemination she will be able to know what tumours are more at risk of becoming metastatic and find new treatments for children and young adults with these cancers. Read more.


Predicting the transmission of rare, genetically based diseases

Researchers have traced the origins of a rare genetic disease to two Quebec founding families in the 17th century

There are only 25 people in the whole of Quebec at the moment who have a rare recessive genetic disease called chronic atrial and intestinal dysrhythmia (CAID). It is a serious disease that affects both heart rate and intestinal movements. A McGill-led research team has been able to trace the gene mutations underlying the disease back to two European founding families who arrived in the province in the 17th century. To track the transmission histories of these rare mutations, the researchers developed a sophisticated computational process, which took two weeks to run, that should help them and others trace a range of other genetically based rare diseases. They hope to extend their search techniques to tracing the transmission histories of more common genetically based diseases in the future and to identify new genetic variants responsible for rare diseases.

Q+ A with lead researchers, Simon Gravel and Dominic Nelson. Read more


Complex Traits celebrates 10 years of discovery in the Life Sciences Complex

Professor of Human Genetics and Theme Lead for the McGill University Research Centre on Complex Traits (MRCCT), Silvia Vidal was recruited to the LSC in 2003 while it was still in the planning stages. When the doors opened in 2008, she immediately launched an ambitious collaboration that took full advantage of the new facilities. Clinician-scientists, infectious disease specialists and computer scientists from the LSC, the McGill University Health Centre, the Faculty of Science, the McGill Genome Centre, and the University of British Columbia were enlisted and the resulting project led to the discovery of a host of new mutations in mouse genes that are now being used to develop molecules to treat diseases like multiple sclerosis, Crohn’s disease, malaria, and other infectious and inflammatory diseases. It was an auspicious beginning, says Professor Vidal. “There are only a few places in the world where it was possible to carry out this very large project, I was very lucky to have been recruited to the LSC,” she says.

Read the full story on Med e-News.


MUHC researchers identify genetic defects that cause molar pregnancies

AARON DERFEL, MONTREAL GAZETTE

Isabelle Lafond lived the nightmare that about 100 pregnant Quebec women do each year, when they discover the fetus is missing or incomplete.

Isabelle Lafond will never forget the day she was told that even though she was pregnant, she wasn’t carrying a fetus.

“It was horrible, like a death,” she recalled of that day two years ago. “I didn’t understand what was happening, what the problem was, why me. Today, it’s still hard to accept.”

Lafond, who is 27, has had two complete molar pregnancies. Instead of a fetus growing inside the uterus, a mole grows inside, and in up to 15 per cent of cases, that mole turns malignant and can cause cancer.

Now scientists at the Research Institute of the McGill University Health Centre have discovered three genetic mutations that are likely to cause a recurrent type of molar pregnancy. The discovery paves the way for better genetic screening, says the lead researcher of a study just published in the American Journal of Human Genetics.

“We’re now in a better position to provide accurate genetic counselling,” said Rima Slim, a geneticist at the MUHC’s research institute. Read more here.


Twenty-three Canada Research Chairs for McGill

Drs. Mark Lathrop, Simon Gravel, Hamed Najafabadi and Silvia Vidal are among McGill’s CRC recipients.

The Government of Canada invests $156 million in funding for 187 new and renewed Canada Research Chairs to support diverse research talent in Canada

On Tuesday, November 13, the Honorable Kirsty Duncan, Minister of Science and Sport, announced over $156 million in funding for 187 new and renewed Canada Research Chairs (CRCs) at universities across Canada. Of the 23 CRCs awarded to McGill researchers, six are new and 17 are renewals.

Read more


Four Burning Questions with Dr. Gustavo Turecki

To mark the 75th anniversary of McGill University’s Department of Psychiatry, Canada’s first academic department in the field, a special symposium will be held at the St. James Theatre on November 29. Under the theme “Looking Forward, Looking Back” the event will provide participants with the opportunity to hear from a distinguished lineup of international speakers and to network with old and new colleagues alike.

To commemorate the milestone the Department has also established a goal to raise $100,000 towards the creation of the Psychiatry 75th Anniversary Fellowship, which will support trainees in the pursuit of excellence related to brain and mental health clinical care, research, education and innovation.

Ahead of the event we sat down with Dr. Gustavo Turecki who has been Chair of the Department of Psychiatry at McGill since 2015 and was recently appointed Chief of Psychiatry at the Montréal West Island IUHSSC and Scientific Director of the Douglas Mental Health University Institute.

Read more.


Far from a classroom exercise happening behind the walls of the ivory tower, university research is a fundamental component of Canada’s economic health – both today and into the future.

Some of our country’s greatest inventions and world-renowned accomplishments, such as canola and insulin, have happened on the nation’s university campuses.

Universities in Canada carry the country’s burden of research and invention, and that burden is made heavier by limited funding from private resources. And, while Canada has contributed many significant discoveries to the world through its academic research, it has also received its fair share of criticism, mainly due to gaps in funding for STEM (Science, Technology, Engineering and Math) research.

The 2017 Canada’s Fundamental Science Review, reports that, “Despite high levels of talent, expertise, and dedication on the part of those serving each agency, there is evidence to suggest that the overall stewardship of the federal research ecosystem needs to be strengthened.”

But there is hope that change is coming. Click here for more.


Scientific breakthrough: promising new target for immunotherapy

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response. Scientists and physicians from the Research Institute of the McGill University Health Centre (RI-MUHC), the Montreal Children’s Hospital of the MUHC (MCH-MUHC) and McGill University, in collaboration with French teams from AP-HP, Inserm, Université Paris-Descartes, Université Paris-Diderot, and the Imagine Institute at the Necker-Enfants Malades hospital, have singled out this protein as the next potential target for immunotherapy treatments in patients with cancer and other diseases.

“This study places the TIM-3 protein at the heart of immune system regulation. We could use it as a target in immunotherapies to trigger enhanced immune responses in patients with cancer and better treat them,” says co-lead author of this study, Dr. Nada Jabado, who is a researcher from the Child Health and Human Development Program at the RI-MUHC and an hemato-oncologist at MCH-MUHC.

Researchers found that when the TIM-3 protein is suppressed or inactive, the immune system becomes completely “unleashed” and T cells are uncontrollably over-activated, resulting in a rare form of lymphoma (a form of cancer that starts in the lymphocytes) called subcutaneous panniculitis T lymphoma (LTSCP). Read more here.


McGill Accomplishments at CAGC

Congratulations to the following McGill faculty and students for their recognition at the annual meeting of the Canadian Association of Genetic Counsellors (CAGC), held last week in St. John’s, Newfoundland.

Janine El Helou, MScRecipient of the 2018 CAGC New Leader Award

Posters:

Addressing barriers for rapid cancer genetic counselling: Triage system for treatment-focused genetic testing” MORGAN Amanda, WONG Nora

“Fetal sex discordance by non-invasive prenatal testing: Current practices and possible explanations” LEVY Tess, HODSON Katherine, POUCHET Carly, FITZPATRICK Jennifer McGill University Health Center, Dynacare, Montreal QC

Platform presentations:

“Incidence and carrier frequency of Tay-Sachs disease in French-Canadians from Quebec: a retrospective analysis covering 24 years (1992-2015)” SILLON Guillaume, ALLARD Pierre, DRURY Stella, DE BIE Isabelle

“A familial investigation of recurrent Osteogenesis Imperfecta over three decades”

Claire BASCUNANA, David ROSENBLATT, Franck RAUCH, Pierre MOFFATT, Francis H. GLORIEUX

Scientific Planning Committee Co-Chair

Laurence Baret, MA, MSc

Congratulations, all!


 

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Funding, Jobs and Other Announcements:

Jobs and Other Opportunities:

  • McGill Doctoral Internship Program offers McGill’s doctoral students at the end of their degree the opportunity to learn and grow outside of academia through a 3-month remunerated internship. Applications accepted on a rolling basis. Click here for testimonials.

Awards – Call for Nominations:

Funding Opportunities

  • Canada Graduate Scholarships -Master’s (CGS M) Funding opportunity for high-calibre scholars who are engaged in eligible master’s or, in some cases, doctoral programs in Canada (refer to Eligibility). See departmental reminders. Deadline: December 1, 2018
  • DAAD (German Academic Exchange Service) is offering Study Scholarships and Research Grants for highly qualified graduate students, PhD candidates, and post-doctoral researchers in all disciplines to study and carry out research at universities or research institutes in Germany. Information session: October 3, 2018 at 10am, RSVP by Sept 12, 2018
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December 2018

  • December 20, 2018 at 10:00am – Visiting Scientist at The Lady Davis Institute Dr. Tim Assimes (Cardiologist and Professor, Stanford University).  Talk entitled: “Polygenic Risk Scores to Predict Coronary Artery Disease: Ready for Prime Time?“.  To be held at the Lady Davis Institute of the Jewish General Hospital, Room H-433
  • January 14, 2018 at 1:30pmMa’n Zawati’s (Centre of Genomics and Policy, Executive Director) Faculty of Law Ph.D. Oral Defence entitled “Of Research Participants and Population Biobanks: Reciprocity as a Conceptual Basis to Relational Autonomy“. Supervisor: Professor Lara Khoury. To be held at Chancellor Day Hall, 3644 Peel Street, NCDH 102
  • January 17, 2019 at 3:00pmShamisa Honarmand’s Ph.D Oral Defence entitled “Molecular mechanisms underlying the pathogenesis of Leigh Syndrome French Canadian“. Supervisor: Dr. Eric Shoubridge. To be held in the Goodman Cancer Research Centre, 1160 Pine Ave West. Rm 501

Call for Travel Awards

The Graduate Training Committee is now soliciting applications for Graduate Travel Awards. Travel awards are not just for research. They could be used for (as examples) learning about research techniques, visiting another lab to collect data with specific tools or expertise available in the host lab, or national or international workshops.

All applications for travel must be held between September 1, 2018 and August 31, 2019. This means you may have already attended the activity and are requesting reimbursement. If this is the case, proof of payment will be required as supporting documentation.

Should you wish to apply to the Annual Canadian and Human Statistical Genetics Meeting (CHSGM), you must submit an application under this Graduate Travel Award Request. The 8th Annual CHSGM will be held in conjunction with the Canadian GE3LS and Health Services and Policy Research Conference on June 16-19, 2019 at Fairmont le Château Montebello, Quebec. Registration will commence January 2019.

All approved requests for a Travel Award will require supervisor acknowledgment and support of your attendance.

The deadline to have an application submitted is January 20, 2019.


Excellence Awards 2018

Excellence awards are given annually, in recognition of extraordinary performance over the academic year. The award is a one-time scholarship payment. Both M.Sc. and Ph.D. students registered full-time through the Department of Human Genetics are eligible to apply. The applications submitted before the deadline will be evaluated by the Graduate Training Committee (GTC) and the results of the competition will be announced in February 2019.

This year, and in company of excellence awards, two independent subsections for acknowledgement have been identified by the GTC and may also to be applied for in parallel and through the same application form:

  • Best Publication Award
  • Department Activity Award

Excellence Award Nomination Forms should be submitted to Ross Mackay and must be received by January 13, 2019.


Science Exposed/La preuve par l’image

The Science Exposed contest welcomes researchers in the public or private sector to submit images in the context of their research either individually or as a group. While organized by NSERC (in collaboration with Acfas for the French segment “La preuve par l’image”), the contest is open to all fields of study.

The contest is open to student researchers at the Master’s or doctoral level, postdoctoral researchers, research professors, and researchers in a public or private research centre. They are invited to submit a single image of their research.

Images can relate to any field of study: natural sciences and engineering, social sciences and humanities, or health sciences, with the exception of images from the arts, including visual arts, media arts, and research/creation. They must be submitted in English or French with a three-part description: a catchy title, a plain-language explanation of the research presented in the image, and a description of the techniques/technologies used to create the image.

NSERC and Acfas will work together to share the winning images with all Canadians.

For more details on the Science Exposed contest, please visit the NSERC website.


Healthy Brains for Healthy Lives -Professional Development Series

Neuroscience lab skills beyond the lab: Effectively presenting your skill set in the job search – Decemeber 4 from 6-8pm

Your graduate studies or postdoctoral experience is teaching you more than just neuroimaging analysis or cellular neuroscience techniques!
You are learning and practising many transferable skills that you can apply in diverse academic and non-academic workplaces. Understanding your skills, and learning how to express them on a CV or at an interview, will help you to succeed in the job market.

Auréliane Pajani, a former cognitive neuroscience researcher turned PhD recruiter at Adoc Talent Management, will introduce the notion of skills and the specific skill set of neuroscience researchers. She will discuss tools to further analyse the skills that you have developed across your work and extra-curricular experiences, and how to present your skills to recruiters. The workshop will be followed by Q&A.

Spaces are limited. Register now to reserve your spot!


Course Offering – Mouse Development, Stem Cells and Cancer

Offered by Cold Spring Harbor Laboratory, this intensive lecture and laboratory course is designed for scientists interested in using mouse models to study mammalian development, stem cells and cancer. The lecture portion of the course, taught by leaders in the field, provides the conceptual basis for contemporary research in embryogenesis, organogenesis in development and disease, embryonic, adult and induced pluripotent stem cells and cancer biology. Takes place  June 5-24, 2019 at Cold Spring Harbor, NY.  Application deadline March 1, 2019. 


87e congrès d’Acfas – appel de propositions: communications libres

Vous êtes à la fin de votre maîtrise, de votre doctorat, ou de votre postdoctorat et vous voulez présenter les résultats de vos recherches au reste de la communauté scientifique? Vous souhaitez faire une communication dans le cadre du prochain Congrès de l’Acfas mais elle ne peut être incluse au sein d’un colloque? Le volet des communications libres est la solution!

Vous avez jusqu’au lundi 10 décembre 2018 pour soumettre votre proposition de communication libre au 87e Congrès de l’Association francophone pour le savoir – Acfas qui se déroulera du 27 au 31 mai 2019 à Université du Québec en Outaouais. Sous le thème « Engager le dialogue savoirs – sociétés », cet évènement sera l’occasion de souligner l’apport des collectivités de la francophonie internationale aux enjeux de la recherche. Au-delà d’une simple diffusion des savoirs, le dialogue engage un échange, une compréhension mutuelle et une appropriation des savoirs au bénéfice de toutes les sociétés.

L’université McGill couvrira les frais d’inscription au congrès et d’adhésion à l’Acfas pour tout 1er auteur (étudiants des cycles supérieures et postdoctorales) d’une proposition de communication libre acceptée.


Technology Day

Dr. Ragoussis is organizing a Technology Day for the Department of Human Genetics in collaboration with the HGSS. The purpose of this is to educate and inform all members of the Department about technologies and methodologies relevant for ongoing research at the Department available at different sites, as well as ones that would be desirable to bring in. It will also serve to bring together students and scientists from the different sites and promote communication and exchange of ideas as well as experiences across sites.

Please help us design this endeavor by completing this survey. Thank you on behalf of Dr. Ragoussis and the HGSS


French Credit Courses – McGill School of Continuing Studies

French for Professional Communication Part-Time Program:  This program is especially designed for people who need French for their work and who hope to use French as an important tool or catalyst for their careers. All Graduate students that are new to the program, and wish to register for the Winter 2019 semester must take an Entrance Placement Test prior to registering for a particular course. Please click the following link to reserve your spot at the next Entrance Placement Test on November 15th: www.mcgill.ca/french-ept (Other dates will be available soon on our page but we encourage you to register ASAP since we have limited spots available: November 21st; December 4th & 11th; late registration: January 3rd) .  Returning students can now register directly on Minerva, or contact our department if you encounter any registration restrictions.

Quebec Tuition Fee Rate  may apply when registering for any French credit courses.  See list of exclusions at https://www.mcgill.ca/student-accounts/tuition-fees/general-tuition-and-fees-information/tuition-fee-exemptions

Please visit our website for more details about our Certificate Program


3rd Annual Graduate Student Recruitment Day – Goodman Cancer Research Centre

McGill’s Goodman Cancer Research Centre (GCRC) is hosting its third annual graduate recruitment event on January 24 and 25, 2019. This event provides prospective students with an opportunity to meet current students and faculty members and receive a one-year studentship to study at the GCRC.  Application deadline: November 12, 2018

More information can be found on our website.

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myProgress – New Degree Milestones Tracking Tool

A NEW web based tool designed to help graduate students navigate their progress through their Master’s or PhD degrees.

Benefits of myProgress

  • See course and program requirements for your McGill degree
  • Monitor your progress towards your degree
  • Receive reminders of upcoming or missed academic milestones in thesis programs

Who can access myProgress?

  • Students who have been admitted to a graduate program in Fall 2017, Winter 2018, Summer 2018 and Fall 2018.
  • Supervisors of students admitted to McGill as of Fall 2017.

How to access myProgress

Students and supervisors can access myProgress by going to https://www.mcgill.ca/gps/myprogress and login using their McGill Username and Password.

Be sure to watch the “myProgress Quick Tour”  video for instructions on how to use myProgress.

Check back often as we update your records towards your degree progression!

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Career Development and Professional Skills for Research Trainees

Presented by the Desjardins Centre for Advanced Training of the RI-MUHC (McGill trainees who are not part of the RI-MUHC are welcome to attend most events and activities).

Sessions include Peer Career Groups: for trainees who want to explore possible careers for health scientists and researchers, Preparing Winning Scholarships and Fellowships, and Developing Your Soft Skills For Today and Tomorrow in an Interconnected Society.

For more information and to register for sessions, click here

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HGEN 698 – Advanced Readings in Genetics

This course aims to familiarize students with the evolving field of epigenetics and
chromatin biology and the role of epigenetics in development and disease.

For more information: HGEN 698 epigenetics_and_chromatin

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GRAPHOS

This fall, Graphos is offering 1-credit, pass/fail courses designed to help students develop clear and coherent manuscripts and oral presentations. Several courses are available and Doctoral students and many Master’s students can take the courses without extra fees, thanks to the University’s tuition sponsorship program.  To see the list of courses see here for more detail.

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