Dr. Svetlana Komarova awarded NSERC Discovery Grant

April 2015

Congratulations to Dr. Svetlana Komarova for being awarded an NSERC Discover Grant for her project “Exploring complex cellular interactions: Mathematical modeling and experimental studies of bone turnover”. Dr. Komarova will receive $28 000 per year for the next five years to use towards her project.

The goal of this research program is to understand how mechanical forces regulate bone cells immediate activity and their ability to perform physiological function, and how physical environment of individual cells is integrated in the performance of bone as an organ. We will examine how individual bone cells, osteoblasts and osteoclasts respond to local membrane deformation, and will assess how focal deformation of a single cell affects neighbouring un-stimulated cells. We will use mathematical modeling to better understand how changes induced in individual cells by mechanical forces are integrated into the tissue scale bone function. Overall, we aim for better understanding of how complex physical and biochemical signals result in time- and position-sensitive changes in the functional bone tissue.

For more information on NSERC Discover Grants visit the NSERC site.

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